Uji Aktivitas Antiinflamasi Ekstrak Kulit Pisang Kepok (Musa Acuminata x Musa Balbisiana) Pada Mencit Jantan (Mus Musculus)

Purba, Sandra (2021) Uji Aktivitas Antiinflamasi Ekstrak Kulit Pisang Kepok (Musa Acuminata x Musa Balbisiana) Pada Mencit Jantan (Mus Musculus). Skripsi thesis, Universitas Kadiri.

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Abstract

Banana peels contain secondary metabolite compounds that can be used as anti-inflammatory. The study aims to test the anti-inflammatory activity of banana peel extract on mice induced 5% egg white solution . Banana peel extract is obtained using the maceration method with a 70% ethanol solvent. Inflammatory power test using edema formation method on the sole of the left foot squeaks by inducing a 5% egg white solution. In this study used experimental research methodology with pretest research design and posttest control design conducted on 25 male mice divided into 5 groups, namely the negative control group Na-CMC 1%, the positive control group of sodium diclofenac suspension, the dose group 100 mg/KgBB, the dose group 200 mg/KgBb, and the dose group 400 mg /KgBB. The observed parameter is the thickness of edema in the soles of the squeaking feet which is measured using a funnel term every 30 minutes for 3 hours. The edema thickness results were used to calculate the AUC (Area Under The Curve) and the percentage of inflammatory power (%DAI), further analyzed with the One Way Anova Test. The results showed that banana peel extract has anti-inflammatory activity, where doses of 400 mg/KgBB have the most effective anti-inflammatory activity. Keywords : Banana peels, Anti-inflammatory, plantar thick plantar mice

Item Type: Thesis (Skripsi)
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Ilmu Kesehatan > Prodi Farmasi S1
Depositing User: NR Nurul Huda
Date Deposited: 02 Mar 2022 04:24
Last Modified: 02 Mar 2022 04:24
URI: http://repository.unik-kediri.ac.id/id/eprint/329

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